The bread guts are not meat in any way, and therefore nutritionally irrelevant. So, out it goes. Throw it in the trash or set it on fire at your leisure. Now, back to meat!
Mix four pounds of ground beef and four eggs in your best beef mixing bowl. Also, some onion or whatever. When mixed, stop mixing. Pour the beef into the bread shell to a depth of two inches, then include six wieners on top of this beef base strata. Also, include a few pickles or small fish (The picture isn't very clear, but play it safe and put in both!). Resume the beef mix inclusion until the beef is completely included in the bread shell.
Replace the bread lid, cover with high quality beef foil and bake at 375 degrees for two hours in your favorite beef oven. The beef will shrink in size as it cooks itself. This extra space will be taken up by the flavor juices that renders out of the beef. It may form pockets in the boundary layer around the wieners and pickles or fish things. This is normal and desirable.
Just wait 'till your family puts a fork in this Loaf Meat! They'll think it's an ordinary bread roast. Then they'll be all "Whoa! Beef!". Then they'll go "Hey! Wieners!" and "Pickles or some small fish I'm not sure! Wow!" and then they'll find the flavor juices and go all "Flavor juice pockets! Slurp!" Mom's meat loaf might as well admit defeat. Mom has surely had it socked to her by this! Loaf Meat's socking-it-to-mom abilities will surely go undoubted! Opa!